hela® medical whitepapers




Collection of clinical studies


Published on Febraury 10, 2016



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Rejuvenation of Gene Expression Pattern of Aged Human Skin by Broadband Light Treatment: A Pilot Study



Anne Lynn S. Chang, Patrick H. Bitter, Kun Qu, Meihong Lin, Nicole A. Rapicavoli, and Howard Y. Change Journal of Investigative Dermatology (2013) 133, 394-402; doi:10.1038/jid.2012.287;


Published on August 30, 2017

UV photoprotection by combination topical antioxidants vitamin C and vitamin E



Lin JY, Selim MA, Shea CR, Grichnik JM, Omar MM, Monteiro-Riviere NA, Pinnell SR. J Am Acad Dermatol. 2003 Jun;48(6):866-74. PMID: 12789176 [PubMed- indexed for MEDLINE]


Increased antioxidant potential of combined topical vitamin E and C against lipid peroxidation of eicosapentaenoic acid in pig skin induced by simulated solar radiation 



Moison Rm, Doerga R, M J Beijersbergen Van Henegouwen G. Int J Radiat Biol. 2002 Dec; 78(12): 1185-93. PMID: 12556345 [PubMed-indexed for MEDLINE]



Ferulic acid stabilizes a solution of vitamins C and E and doubles its photoprotection of skin



Lin FH, Lin JY, Gupta RD, Tournas JA, Burch JA, Selim MA, Monteiro-Riviere NA, Grichnik JM, Zielinski J, Pinell Sr. J Invest Dermatol. 2005 Oct; 125(4):825-32. PMID: 16185284 [PubMed- indexed for MEDLINE]


Topical isoflavones provide effective phptoprotection to skin



Lin JY, Tournas JA, Burch JA, Montiero-Riviere NA, Zielinski J. Phtodermatol Photoimmunol Photomed. 2008 Apr;24(2): 61-6. doi: 10.1111/j.1600-0781.2008.00329.x. PMID: 18353084 [PubMed- indexed for MEDLINE]



Hydoxocobalamin (Vitamin B12) Injection



Most vitamin B12 injections and oral supplements in the United STates use a form of vitamin B12 called cyanocobalamin, however this form of vitamin B12 has the toxin cyanide connected to the molecule. Cyanide is a toxic substance to the human body; it can be found in trace amounts in our environment and accumulate in our body over time...


Hyperhidrosis: Anatomy, Pathophysiology and Treatment with Emphasis on the Role of Botulinum Toxins 



Lakraj A-AD, Moghimi N, Jabbari B. Toxins. 2013; 5(4): 821-840. 



J Drugs in Dermatol - product for pigmentation control



Skin conditions related to hyperpigmentation continue to contribute to psychosocial anxiety that lead to poor quality-of-life measures. Pigmentary changes are the first sign of aging in...


Review The Roles of Vitamin C in Skin Health



The primary function of the skin is to act as a barrier against insults from the environment, and its unique structure reflects this. The skin is composed of two layers...





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